FAQs

Frequently Asked Questions

  • What is the approved use for TRELEGY 100/62.5/25 mcg for COPD?

    TRELEGY 100/62.5/25 mcg is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD). COPD is a chronic lung disease that includes chronic bronchitis, emphysema, or both. TRELEGY is used long term as 1 inhalation 1 time each day to improve symptoms of COPD for better breathing and to reduce the number of flare-ups (the worsening of your COPD symptoms for several days). TRELEGY is not used to relieve sudden breathing problems and won't replace a rescue inhaler.

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  • How do I know if I need more from my daily COPD medicine?

    If you've been using a daily maintenance medicine to treat your COPD and still have trouble breathing or experience flare-ups (exacerbations), you may want your COPD treatment to do more. Talk to your doctor about 3-in-1 TRELEGY and ask if it can do more to treat your COPD. TRELEGY 100/62.5/25 mcg is the only FDA-approved complete once-daily maintenance treatment with 3 types of long-acting COPD medicines working together in 1 inhaler to improve breathing for a full 24 hours. Your results may vary. TRELEGY does not replace a rescue inhaler.

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  • What does 3-in-1 TRELEGY mean for me?

    TRELEGY 100/62.5/25 mcg is the only FDA-approved 3-in-1 once-daily maintenance treatment. The 3 long-acting COPD medicines in 1 inhaler, taken daily, help prevent symptoms from occurring.

    In studies, patients taking TRELEGY had improved lung function vs patients taking 2 of TRELEGY's 3 medicines. TRELEGY has the power of 3 medicines that work 3 ways to open airways, keep them open, and reduce inflammation for 24 hours of better breathing. Your results may vary. TRELEGY does not replace a rescue inhaler.

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  • What are the 3 medicines in TRELEGY?

    TRELEGY 100/62.5/25 mcg is the only FDA-approved 3-in-1 once-daily maintenance triple therapy for COPD. TRELEGY contains 3 long-acting medicines: fluticasone furoate (an inhaled corticosteroid [ICS]), umeclidinium (a long-acting muscarinic antagonist [LAMA] also known as an anticholinergic), and vilanterol (a long-acting beta2-adrenergic agonist [LABA]).

    To understand more about what each medicine does, click here.

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  • How does TRELEGY help me breathe better?

    TRELEGY 100/62.5/25 mcg is the only FDA-approved once-daily COPD medicine that combines 3 separate long-acting medicines in 1 inhaler. TRELEGY works to open airways, keep them open, and reduce inflammation for a full 24 hours of better breathing. Taking TRELEGY every day provides a long-acting, daily maintenance medication to help prevent symptoms from occurring (such as wheezing, coughing, chest tightness, and shortness of breath). Your results may vary.

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  • Does TRELEGY treat sudden symptoms of COPD?

    No. TRELEGY 100/62.5/25 mcg is used long term as a once-daily medication to help prevent symptoms of COPD for better breathing and to reduce the number of flare-ups. TRELEGY does not relieve sudden symptoms of COPD, and you should not take extra doses of TRELEGY to relieve these sudden symptoms. Always have a rescue inhaler (an inhaled, short-acting bronchodilator) with you to treat sudden symptoms. If you do not have a rescue inhaler, contact your healthcare provider to have one prescribed for you.

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  • Should I stop taking TRELEGY if my symptoms get better?

    Do not stop using TRELEGY unless told to do so by your healthcare provider, because your symptoms might get worse. Your healthcare provider will change your medicines as needed. 

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  • When should I take TRELEGY?

    Use 1 inhalation of TRELEGY 1 time each day. Use TRELEGY at the same time each day. If you miss a dose of TRELEGY, take it as soon as you remember. Do not take more than 1 inhalation per day. Take your next dose at your usual time. Do not take 2 doses at 1 time.

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  • How do I store TRELEGY?

    Store TRELEGY at room temperature between 68°F and 77°F (20°C and 25°C). Keep in a dry place away from heat and sunlight. Store TRELEGY in the unopened foil tray and only open when ready for use.

    Safely throw TRELEGY away in the trash 6 weeks after you open the foil tray or when the counter reads "0," whichever comes first. Write the date you open the tray on the label on the inhaler.

    Keep TRELEGY and all medicines out of the reach of children.

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  • When should TRELEGY ELLIPTA NOT be used?

    Do not use TRELEGY to treat sudden, severe symptoms of COPD or asthma. Do not use TRELEGY if you have a severe allergy to milk proteins. Ask your healthcare provider if you are not sure. Do not use TRELEGY if you are allergic to fluticasone furoate, umeclidinium, vilanterol, or any of the ingredients in TRELEGY.

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  • What should I tell my doctor before using TRELEGY?

    Tell your healthcare provider about all of your medical conditions, including if you:

    • have heart problems.
    • have high blood pressure.
    • have seizures.
    • have thyroid problems.
    • have diabetes.
    • have liver problems.
    • have weak bones (osteoporosis).
    • have an immune system problem.
    • have eye problems such as glaucoma, increased pressure in your eye, cataracts, blurred vision, or other changes in vision. TRELEGY ELLIPTA may make your glaucoma worse.
    • are allergic to milk proteins. 
    • have prostate or bladder problems, or problems passing urine. TRELEGY ELLIPTA may make these problems worse.
    • have any type of viral, bacterial, parasitic, or fungal infection.
    • are exposed to chickenpox or measles.
    • are pregnant or plan to become pregnant. It is not known if TRELEGY ELLIPTA may harm your unborn baby.
    • are breastfeeding. It is not known if the medicines in TRELEGY ELLIPTA pass into your milk and if they can harm your baby.


    Tell your healthcare provider about all the medicines you take,
     including prescription and over-the-counter medicines, vitamins, and herbal supplements. TRELEGY ELLIPTA and certain other medicines may interact with each other. This may cause serious side effects.

    Especially tell your healthcare provider if you take: 

    • anticholinergics (including tiotropium, ipratropium, aclidinium)
    • atropine
    • other LABA (including salmeterol, formoterol, arformoterol, olodaterol, and indacaterol)
    • antifungal or anti-HIV medicines


    Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

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  • Is this inhaler recyclable?

    GSK cannot guarantee that TRELEGY ELLIPTA inhalers or their contents can be fully recycled. Because waste disposal laws and regulations vary from state to state, check with your local or state government agency for guidance.

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Using TRELEGY

  • How do I use the TRELEGY ELLIPTA inhaler?

    You can see a demonstration of how to take a dose and read the step-by-step Instructions for Use for TRELEGY here. If you need more help, talk to your doctor or pharmacist.

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  • How do I know I've received the dose?

    After you slide the cover down to expose the mouthpiece, you should hear a "click," and the dose counter will decrease by 1. Even when using the inhaler correctly, you may not taste or feel the medicine and you should not take another dose. 

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  • Why does the dose counter start at 30 instead of 60?

    • Each inhaler of TRELEGY contains 30 doses, which equals a 30-day supply. That's why your dose counter starts at 30, and counts down with each dose.
    • TRELEGY contains 3 medicines. Inside the inhaler, the 3 medicines are packaged into 2 separate strips that each contain 30 blisters. When you open the inhaler (and hear the click), the contents of 1 blister from each of the 2 strips combine to form 1 dose of TRELEGY.
    • You may see the quantity "60" mentioned in printouts about your prescription, but your inhaler provides 30 doses. The "60" refers to the number of blisters inside the inhaler, and not the number of doses.

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Payments & Savings for TRELEGY