Trelegy FAQs

Frequently Asked Questions

WHAT IS THE APPROVED USE FOR TRELEGY?

TRELEGY is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD). COPD is a chronic lung disease that includes chronic bronchitis, emphysema, or both. TRELEGY is used long term as 1 inhalation 1 time each day to improve symptoms of COPD for better breathing and to reduce the number of flare-ups (the worsening of your COPD symptoms for several days). TRELEGY is not used to relieve sudden breathing problems and won't replace a rescue inhaler. TRELEGY is not for the treatment of asthma.

HOW DO I KNOW IF I NEED MORE FROM MY DAILY COPD MEDICINE?

If you've been using a daily maintenance medicine to treat your COPD and still have trouble breathing or experience flare-ups, you may want your COPD treatment to do more. Talk to your doctor about 3-in-1 TRELEGY and ask if it can do more to treat your COPD. TRELEGY is the only FDA-approved complete maintenance treatment with 3 types of long-acting COPD medicines working together in 1 inhaler to improve breathing for a full 24 hours.

Your results may vary. TRELEGY does not replace a rescue inhaler.

WHAT DOES TRELEGY'S POWER OF 1 2 3 MEAN FOR ME?

In studies, patients taking TRELEGY had improved lung function vs patients taking 2 of TRELEGY's 3 medicines. TRELEGY has the power of 3 medicines that work 3 ways to open airways, keep airways open, and reduce inflammation for 24 hours of better breathing. Your results may vary. TRELEGY does not replace a rescue inhaler.

TRELEGY is the only FDA-approved 3-in-1 maintenance treatment. The 3 long-acting medicines in 1 inhaler, taken daily, help prevent symptoms from occurring.

ARE THERE SAVINGS OFFERS FOR TRELEGY?

Yes, you may be eligible to pay no more than $10 a month for up to 12 months. To find out if you qualify for savings, read the .

WHAT ARE THE 3 MEDICINES IN TRELEGY?

TRELEGY is the only FDA-approved, 3-in-1 maintenance triple therapy for COPD. TRELEGY contains 3 long-acting medicines: fluticasone furoate (an inhaled corticosteroid [ICS]), umeclidinium (a long-acting muscarinic antagonist [LAMA]), and vilanterol (a long-acting beta2-adrenergic agonist [LABA]).

To understand more about what each medicine does, click here.

HOW DOES TRELEGY HELP ME BREATHE BETTER?

TRELEGY is the only FDA-approved COPD medicine that combines 3 separate long-acting medicines in 1 inhaler. TRELEGY works to open airways, keep them open, and reduce inflammation for a full 24 hours of better breathing. Taking TRELEGY every day provides a long-acting, daily maintenance medication to help prevent symptoms from occurring (such as wheezing, coughing, chest tightness, and shortness of breath). Your results may vary.

HOW DO I USE TRELEGY ELLIPTA?

You can see a demonstration of how to take a dose here. You can read the step-by-step Instructions for Use for TRELEGY here. If you need more help, talk to your doctor or pharmacist.

DOES TRELEGY TREAT SUDDEN SYMPTOMS OF COPD?

No. TRELEGY is used long term as a once-daily medication to help prevent symptoms of COPD for better breathing and to reduce the number of flare-ups. TRELEGY does not relieve sudden symptoms of COPD, and you should not take extra doses of TRELEGY to relieve these sudden symptoms. Always have a rescue inhaler (an inhaled, short-acting bronchodilator) with you to treat sudden symptoms. If you do not have a rescue inhaler, contact your healthcare provider to have one prescribed for you.

SHOULD I STOP TAKING TRELEGY IF MY SYMPTOMS GET BETTER?

Do not stop using TRELEGY unless told to do so by your healthcare provider because your symptoms might get worse. Your healthcare provider will change your medicines as needed.

WHEN SHOULD I TAKE TRELEGY?

Use 1 inhalation of TRELEGY 1 time each day. Use TRELEGY at the same time each day. If you miss a dose of TRELEGY, take it as soon as you remember. Do not take more than 1 inhalation per day. Take your next dose at your usual time. Do not take 2 doses at 1 time.

HOW DO I KNOW I'VE RECEIVED THE DOSE?

After you slide the cover down to expose the mouthpiece, you should hear a "click," and the dose counter will decrease by 1. Even when using the inhaler correctly, you may not taste or feel the medicine and should not take another dose.

I THOUGHT THE INHALER CONTAINED 60 DOSES OF MEDICINE. WHY DOES THE DOSE COUNTER START AT 30 INSTEAD OF 60?

  • Each inhaler of TRELEGY contains 30 doses, which equals a 30-day supply. That's why your dose counter starts at 30.
  • TRELEGY contains 3 medicines. Inside the inhaler, the 3 medicines are packaged into 2 separate strips that each contain 30 blisters. When you open the inhaler (and hear the click), the contents of 1 blister from each of the 2 strips combine to form 1 dose of TRELEGY.
  • You may see the quantity "60" mentioned in printouts about your prescription, but your inhaler provides 30 doses. The "60" refers to the number of blisters inside the inhaler, and not the number of doses.

HOW DO I STORE TRELEGY?

Store TRELEGY at room temperature between 68°F and 77°F (20°C and 25°C). Keep in a dry place away from heat and sunlight.

Store TRELEGY in the unopened foil tray and only open when ready for use.

Safely throw away TRELEGY in the trash 6 weeks after you open the foil tray or when the counter reads "0," whichever comes first. Write the date you open the tray on the label on the inhaler.

Keep TRELEGY and all medicines out of the reach of children.

WHO SHOULD NOT USE TRELEGY?

Do not use TRELEGY if you have a severe allergy to milk proteins. Ask your healthcare provider if you are not sure. Do not use TRELEGY if you are allergic to fluticasone furoate, umeclidinium, vilanterol, or any of the ingredients in TRELEGY.

WHAT SHOULD I TELL MY DOCTOR BEFORE USING TRELEGY?

Tell your healthcare provider about all of your medical conditions, including if you:

  • have heart problems.
  • have high blood pressure.
  • have seizures.
  • have thyroid problems.
  • have diabetes.
  • have liver problems.
  • have weak bones (osteoporosis).
  • have an immune system problem.
  • have eye problems such as glaucoma or cataracts. TRELEGY ELLIPTA may make your glaucoma worse.
  • are allergic to milk proteins.
  • have prostate or bladder problems, or problems passing urine. TRELEGY ELLIPTA may make these problems worse.
  • have any type of viral, bacterial, parasitic, or fungal infection.
  • are exposed to chickenpox or measles.
  • are pregnant or plan to become pregnant. It is not known if TRELEGY ELLIPTA may harm your unborn baby.
  • are breastfeeding. It is not known if the medicines in TRELEGY ELLIPTA pass into your milk and if they can harm your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. TRELEGY ELLIPTA and certain other medicines may interact with each other. This may cause serious side effects.

Especially tell your healthcare provider if you take:

  • anticholinergics (including tiotropium, ipratropium, aclidinium)
  • atropine
  • other LABA (including salmeterol, formoterol, arformoterol, olodaterol, and indacaterol)
  • antifungal or anti-HIV medicines.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

IS THIS INHALER RECYCLABLE?

GSK cannot guarantee that ELLIPTA inhalers or their contents can be fully recycled. Because waste disposal laws and regulations vary from state to state, check with your local or state government agency for guidance.

Important Safety Information

  • TRELEGY is not for asthma. TRELEGY contains vilanterol. Long-acting beta2-adrenergic agonist (LABA) medicines such as vilanterol when used alone increase the risk of hospitalizations and death from asthma problems. TRELEGY contains an inhaled corticosteroid (ICS), an anticholinergic, and a LABA. When an ICS and LABA are used together, there is not a significant increased risk in hospitalizations and death from asthma problems.

Important Safety Information

  • TRELEGY is not for asthma. TRELEGY contains vilanterol. Long-acting beta2-adrenergic agonist (LABA) medicines such as vilanterol when used alone increase the risk of hospitalizations and death from asthma problems. TRELEGY contains an inhaled corticosteroid (ICS), an anticholinergic, and a LABA. When an ICS and LABA are used together, there is not a significant increased risk in hospitalizations and death from asthma problems.
  • Do not use TRELEGY to relieve sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.
  • Do not use TRELEGY if you have a severe allergy to milk proteins or are allergic to any of the ingredients in TRELEGY. Ask your healthcare provider if you are not sure.
  • Do not use TRELEGY more often than prescribed.
  • Do not take TRELEGY with other medicines that contain a LABA or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take.
  • Call your healthcare provider or get medical care right away if your breathing problems get worse, if you need your rescue inhaler more often than usual or it does not work as well to relieve your symptoms.
  • TRELEGY can cause serious side effects, including:
    • fungal infection in your mouth or throat (thrush). Rinse your mouth with water without swallowing after using TRELEGY to help reduce your chance of getting thrush.
    • pneumonia. People with COPD have a higher chance of getting pneumonia. TRELEGY may increase the chance of getting pneumonia. Call your healthcare provider if you notice any of the following symptoms: change in amount or color of mucus; fever; chills; increased cough; increased breathing problems.
    • weakened immune system and increased chance of getting infections.
    • reduced adrenal function. This can happen when you stop taking oral corticosteroids and start taking inhaled corticosteroids.
    • sudden breathing problems immediately after inhaling TRELEGY. If this happens, stop taking TRELEGY and call your healthcare provider right away.
    • serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms: rash; hives; swelling of your face, mouth, and tongue; breathing problems.
    • effects on heart: increased blood pressure; a fast or irregular heartbeat, awareness of heartbeat; chest pain.
    • effects on nervous system: tremor; nervousness.
    • bone thinning or weakness (osteoporosis).
    • new or worsened eye problems, including vision changes or eye pain. You should have regular eye exams while using TRELEGY. If you have symptoms including vision changes, eye pain, nausea, or vomiting, stop taking TRELEGY and call your healthcare provider right away.
    • new or worse urinary retention. Symptoms may include: difficult, painful, or frequent urination; urination in a weak stream or drips. If you have these symptoms, stop taking TRELEGY and call your healthcare provider right away.
    • changes in laboratory blood values, including high levels of blood sugar and low levels of potassium.
  • Common side effects of TRELEGY include: upper respiratory tract infection; pneumonia; bronchitis; thrush in your mouth and throat (rinse your mouth with water without swallowing after use to help prevent this); headache; back pain; joint pain; flu; inflammation of the sinuses; runny nose and sore throat; taste disturbance; constipation; painful and frequent urination (signs of a urinary tract infection); nausea, vomiting, and diarrhea; mouth and/or throat pain; cough; and hoarseness.

Please see full Prescribing Information, including Patient Information, for TRELEGY.

You are encouraged to report negative side effects of prescription drugs to the FDA.Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.