UNDERSTANDING COPD

WHAT YOU NEED TO KNOW ABOUT LIVING WITH COPD

While you may be doing things to improve your condition like getting regular exercise, eating healthier, or quitting smoking, you may want to ask your doctor about treatment options that can help you breathe better. Since chronic obstructive pulmonary disease (COPD) affects everyone differently, your treatment plan may be different from the plan of someone else who has COPD. You and your doctor should work together to decide on a treatment plan that's right for you.

Symptoms of COPD

COPD symptoms can evolve over time, impacting your day-to-day activity level and life. Managing these symptoms can be challenging, but with an effective treatment plan, you can face your COPD head on. It's important to know the symptoms you may experience.

Difficulty breathing

You may experience a shortness of breath and/or wheezing during normal activity or while at rest.

Chest tightness

You may have the feeling that something is squeezing or sitting on your chest, making it hard to breathe.

Coughing up mucus

You may experience a change in the amount or color of mucus coughed up.

Flare-ups: worsening of symptoms

Your symptoms (difficulty breathing, chest tightness, and coughing up mucus) may be worse than usual for several days and require steroids (like prednisone), antibiotics, and/or an emergency room or hospital stay.

Make the most of your next visit to the doctor

When you visit your doctor, you want to talk openly about your COPD, including chronic bronchitis, emphysema, or both, by discussing how it's impacting your life. So take charge and know what you want to talk about, with the help of this discussion guide.

Once-daily TRELEGY is a prescription medicine used long term to treat COPD, including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won't replace a rescue inhaler. TRELEGY is not for asthma.

Important Safety Information

  • TRELEGY is not for asthma. TRELEGY contains vilanterol. Long-acting beta2-adrenergic agonist (LABA) medicines such as vilanterol when used alone increase the risk of hospitalizations and death from asthma problems. TRELEGY contains an inhaled corticosteroid (ICS), an anticholinergic, and a LABA. When an ICS and LABA are used together, there is not a significant increased risk in hospitalizations and death from asthma problems.

Important Safety Information

  • TRELEGY is not for asthma. TRELEGY contains vilanterol. Long-acting beta2-adrenergic agonist (LABA) medicines such as vilanterol when used alone increase the risk of hospitalizations and death from asthma problems. TRELEGY contains an inhaled corticosteroid (ICS), an anticholinergic, and a LABA. When an ICS and LABA are used together, there is not a significant increased risk in hospitalizations and death from asthma problems.
  • Do not use TRELEGY to relieve sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.
  • Do not use TRELEGY if you have a severe allergy to milk proteins or are allergic to any of the ingredients in TRELEGY. Ask your healthcare provider if you are not sure.
  • Do not use TRELEGY more often than prescribed.
  • Do not take TRELEGY with other medicines that contain a LABA or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take.
  • Call your healthcare provider or get medical care right away if your breathing problems get worse, if you need your rescue inhaler more often than usual or it does not work as well to relieve your symptoms.
  • TRELEGY can cause serious side effects, including:
    • fungal infection in your mouth or throat (thrush). Rinse your mouth with water without swallowing after using TRELEGY to help reduce your chance of getting thrush.
    • pneumonia. People with COPD have a higher chance of getting pneumonia. TRELEGY may increase the chance of getting pneumonia. Call your healthcare provider if you notice any of the following symptoms: change in amount or color of mucus; fever; chills; increased cough; increased breathing problems.
    • weakened immune system and increased chance of getting infections.
    • reduced adrenal function. This can happen when you stop taking oral corticosteroids and start taking inhaled corticosteroids.
    • sudden breathing problems immediately after inhaling TRELEGY. If this happens, stop taking TRELEGY and call your healthcare provider right away.
    • serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms: rash; hives; swelling of your face, mouth, and tongue; breathing problems.
    • effects on heart: increased blood pressure; a fast or irregular heartbeat, awareness of heartbeat; chest pain.
    • effects on nervous system: tremor; nervousness.
    • bone thinning or weakness (osteoporosis).
    • new or worsened eye problems, including vision changes or eye pain. You should have regular eye exams while using TRELEGY. If you have symptoms including vision changes, eye pain, nausea, or vomiting, stop taking TRELEGY and call your healthcare provider right away.
    • new or worse urinary retention. Symptoms may include: difficult, painful, or frequent urination; urination in a weak stream or drips. If you have these symptoms, stop taking TRELEGY and call your healthcare provider right away.
    • changes in laboratory blood values, including high levels of blood sugar and low levels of potassium.
  • Common side effects of TRELEGY include: upper respiratory tract infection; pneumonia; bronchitis; thrush in your mouth and throat (rinse your mouth with water without swallowing after use to help prevent this); headache; back pain; joint pain; flu; inflammation of the sinuses; runny nose and sore throat; taste disturbance; constipation; painful and frequent urination (signs of a urinary tract infection); nausea, vomiting, and diarrhea; mouth and/or throat pain; cough; and hoarseness.

Please see the full Prescribing Information, including Patient Information, for TRELEGY.

You are encouraged to report negative side effects of prescription drugs to the FDA.Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.